Multiscale modeling of nanocarrier (NC) hydrodynamics in blood flow

نویسندگان

  • Helena Vitoshkin
  • Yaohong Wang
  • Hsiu-Yu Yu
  • Natesan Ramakrishnan
  • David M. Eckmann
  • Ravi Radhakrishnan
  • Portonovo S. Ayyaswamy
چکیده

Nanocarrier (NC) transport in blood vessels involves hydrodynamic and thermodynamic interactions, which collectively dictate efficacy in targeted drug delivery applications. We investigate two important transport effects of (1) the effect of blood particulates in defining the hydrodynamic fields in simple and complex vascular geometries, and (2) hydrodynamic interactions for NCs of complex shapes.

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تاریخ انتشار 2014